Publications

 

Archival Publications

*Authors contributed equally. Corresponding author.

26. Heyde, K.C. and Ruder,W.C. Programming Biomaterial Interactions Using Engineered Living Cells. Methods in Molecular Biology. (Invited Chapter, In Revision)

25. Scott, F.Y., Heyde, KC., Rice, M.J.K., and Ruder, W.C. Spatial Segregation of Synthetic Circuit Output Using the Cell Surface.  (In Revision)

24. Wolozny, D., Lake, J.R., and Ruder, W.C. An Additive Manufacturing Approach that Enables the Safer Use of Synthetic Biosensors.  (In Revision)

23. Lake, J.R., Heyde, K.C., and Ruder, W.C. Low-Cost Feedback-Controlled Syringe Pressure Pumps for Microfluidics Applications. PLoS ONE. 12(4), 2017. doi: 10.1371/journal.pone.0175089 (Link to paper)

22. Heyde, K.C.*, Rice, M.J.K.*, Paek, S.H., Scott, F.Y., Zhang, R., and Ruder, W.C. Modeling Information Exchange between Living and Artificial Cells. Quantitative Biology. 5:76, 2017. doi:10.1007/s40484-017-0095-4 (Link to paper)

21. Heyde, K.C. and Ruder, W.C. A Model of a Synthetic Biological Communication Interface between Mammalian Cells and Mechatronic Systems. IEEE Transactions on NanoBioscience. 15, 864-870, 2016. doi:10.1109/Tnb.2016.2620942 (Link to paper)

20. Sanjana, N. et al. Principles of Systems Biology-No. 10. Cell Systems 3, 318-320, 2016. (Link to paper)

19. Heyde, K. C., Scott, F. Y., Paek, S. H., Zhang, R., Ruder, W. C. Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials. J. Vis. Exp. (121), e55300, (2017). doi:10.3791/55300 (Link to paper)

18. Heyde, K.C., Gallagher, P.W., and Ruder, W.C. Bioinspired Decision Architectures Containing Host and Microbiome Processing Units. Bioinspiration & Biomimetics. 11, 2016. doi:10.1088/1748-3190/11/5/056017 (Link to paper)

17. Zhang, R.*, Heyde, K.C.*, Scott, F.Y., Paek, S.H., and Ruder, W.C. Programming Surface Chemistry with Engineered Cells. ACS Synthetic Biology. 5, 936-941, 2016. doi:10.1021/acssynbio.6b00037 (Link to paper)

16. Heyde, K.C. and Ruder, W.C.Exploring Host-Microbiome Interactions using an in Silico Model of Biomimetic Robots and Engineered Living Cells. Scientific Reports. 5, 2015. doi:10.1038/srep11988 (Link to paper)

15. Paek, S.H. and Ruder, W.C. 2014. Synthetic Biology Approaches to Cell Therapy. Reviews in Cell Biology and Molecular Medicine. 1–29. (Link to paper)

14. González, L.M., Ruder, W.C., Mitchell, A.P., Messner, W.C., and Leduc, P.R. Sudden Motility Reversal Indicates Sensing of Magnetic Field Gradients in Magnetospirillum magneticum AMB-1 strain. The ISME Journal. 9, 1399-1409, 2015. doi:10.1038/ismej.2014.224 (Link to paper)

13. González, L.M., Ruder, W.C., Leduc, P.R., and Messner, W.C. Controlling magnetotactic bacteria through an integrated nanofabricated metallic island and optical microscope approach. Scientific Reports. 4, 2014. doi:10.1038/srep04104 (Link to paper)

12. Rice, M.J.K. and Ruder, W.C.Creating biological nanomaterials using synthetic biology. Science and Technology of Advanced Materials. 15, 2014. doi:10.1088/1468-6996/15/1/014401 (Link to paper)

11. Ruder, W.C., and Leduc, P.R. Cells gain traction in 3D. Proceedings of the National Academy of Sciences USA. 109, 11060-11061, 2012. doi:10.1073/pnas.1208617109 (Link to paper)

10. Ruder, W.C., Hsu, C.-P.D., Edelman, B.D., Schwartz, R., and LeDuc, P.R.Biological Colloid Engineering: Self-Assembly of Dipolar Ferromagnetic Chains in a Functionalized Biogenic Ferrofluid. Applied Physics Letters. 101, 2012. doi: 10.1063/1.4742329 (Link to paper)

9. Ruder, W.C., Pratt, E.D., Brandy, N.Z.D., LaVan, D.A., LeDuc, P.R., and Antaki, J.F. Calcium signaling is gated by a mechanical threshold in three-dimensional environments. Scientific Reports. 2, 2012. doi:10.1038/srep00554 (Link to paper)

8. Ruder, W.C., Pratt, E.D., Bakhru, S., Sitti, M., Zappe, S., Cheng, C.M., Antaki, J.F., and LeDuc, P.R. Three-Dimensional Polymeric Microfiber Devices with Minimal Feature Profiles for Probing Cell Mechanics and Signaling. Lab on a Chip. 12, 1775-1779, 2012. doi:10.1039/c2lc21117c (Link to paper)

7. Denny, M., Dorgan, K.M., Evangelista, D., Hettinger, A., Leichter, J., Ruder, W.C., and Tuval, I. Anchor Ice and Benthic Disturbance in Shallow Antarctic Waters: Interspecific Variation in Initiation and Propagation of Ice Crystals. The Biological Bulletin. 221, 155-163, 2011. (Link to paper)

6. Ruder, W.C.*, Lu, T.*, and Collins, J.J. Synthetic Biology Moving into the Clinic. Science. 333, 1248-1252, 2011. doi:10.1126/science.1206843 (Link to paper)

5. Ruder, W.C., and Leduc, P.R. Bioinspirations: Cell-Inspired Small-Scale Systems for Enabling Studies in Experimental Biomechanics. Integrative and Comparative Biology. 51, 133-141, 2011. doi:10.1093/icb/icr010 (Link to paper)

4. Kuczenski, B., Ruder, W.C., Messner, W.C., and LeDuc, P.R.Probing Cellular Dynamics with a Chemical Signal Generator. PLoS ONE. 4, 2009. doi:10.1371/journal.pone.0004847 (Link to paper)

3. Zhang, Y.*, Ruder, W.C.*, LeDuc, P.R. Artificial cells: building bioinspired systems using small-scale biology. Trends in Biotechnology. 26, 14-20, 2008. doi:10.1016/j.tibtech.2007.09.006 (Link to paper)

2. Gerbino, A.,Ruder, W.C., Curci, S., Pozzan, T., Zaccolo, M., Hofer, A.M. Termination of cAMP signals by Ca2+ and Gα,i via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillations. Journal of Cell Biology. 171, 303-312, 2005. doi:DOI 10.1083/jcb.200507054 (Link to paper)

1. Lau, B.W., Colella, M., Ruder, W.C., Ranieri, M., Curci, S., and Hofer, A.M. Deoxycholic Acid Activates PKC and PLC through Increased Ca2+ Entry at the Plasma Membrane. Gastroenterology. 128, 695-707, 2005. doi:10.1053/j.gastro.2004.12.046 (Link to paper)